Histological Evaluation of Guided Bone Regeneration in Osseous Defects Using A Novel Non-Resorbable Membrane
نویسندگان
چکیده
BACKGROUND: Guided bone regeneration and guided tissue procedures have been performed using barrier membranes in clinical dentistry to enhance formation osseous defects, ridge preservation reconstruction. Despite the considerable number of new biomaterials that develop with more advantages fewer disadvantages for regeneration, cost surgical approach difficulties are still main obstacles we tried overcome novel membrane. AIM: Our research aimed assess histologically membrane experimental defects. MATERIAL AND METHODS: study was conducted on ten mongrel dogs. Each animal presented two groups. The first group at left side mandible which received Bio-Oss only while right covered by non-resorbable These dogs were sacrificed (3, 6, 9 12 weeks) postoperatively histological assessment healing RESULTS: evaluation showed I (Bio-OSS only) less amount as compared II (Bio-Oss membrane). CONCLUSION: present findings revealed inert induced no inflammatory reaction or graft rejection. provided evidence close contact host due osteoconductivity cell occlussiveness
منابع مشابه
Guided bone regeneration using resorbable membrane and different bone substitutes: Early histological and molecular events.
UNLABELLED Bone insufficiency remains a major challenge for bone-anchored implants. The combination of guided bone regeneration (GBR) and bone augmentation is an established procedure to restore the bone. However, a proper understanding of the interactions between the bone substitute and GBR membrane materials and the bone-healing environment is lacking. This study aimed to investigate the earl...
متن کامل[Histopathological evaluation of bone regeneration using human resorbable demineralized membrane].
BACKGROUND/AIM Filling a bone defect with bone substitution materials is a therapy of choice, but the infiltration of connective tissue from the mucoperiostal flap may compromise a healing of bone substitutions with bony wall defects. Application of membrane as a barrier is indicated as a solution to this problem. The aim of this study was to show a pathohistological view of bone regeneration a...
متن کاملGuided bone regeneration in rat mandibular defects using resorbable poly(trimethylene carbonate) barrier membranes.
The present study evaluates a new synthetic degradable barrier membrane based on poly(trimethylene carbonate) (PTMC) for use in guided bone regeneration. A collagen membrane and an expanded polytetrafluoroethylene (e-PTFE) membrane served as reference materials. In 192 male Sprague-Dawley rats, a standardized 5.0mm circular defect was created in the left mandibular angle. New bone formation was...
متن کاملNovel membrane for guided bone regeneration.
Membranes have been clinically used for guided tissue and bone regeneration for decades, but their use in every day clinical practice is rather limited. We developed a biodegradable membrane (InionGTR) composed of polylactide, polyglycolide and trimethylene carbonate aiming to improve the properties of membrane. Before application the membrane is treated with N-methyl-pyrrolidone (NMP) to achie...
متن کاملGuided bone regeneration (GBR) on healing bone defects: a histological study in rabbits.
In this study, the effects of guided bone regeneration (GBR) on the healing of bone defects were evaluated. Resorbable membranes were placed in experimentally formed cavities in the right posterior tibia of 30 rabbits. Decalcified histological sections were evaluated using optical microscopy at 10, 20, and 30 days after GBR. Osteocondrial bone union, active bone formation and spongiosal bone fo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Open Access Macedonian Journal of Medical Sciences
سال: 2022
ISSN: ['1857-9655']
DOI: https://doi.org/10.3889/oamjms.2022.8262